Quiz on Helmenthiasis Chemotherapy

Helmenthiasis is a disease which is caused by the worms like pinworm, roundworm or tapeworm.

This is the quiz on helmenthiasis chemotherapy. A score above 80% will ensure that you have good knowledge about this topic.

More than one option can be correct in any given question.

1. Which part of the body does this disease affects?
   1. Urogenital tract
   2. Gastrointestinal tract
   3. Nervous system
   4. Skeletal system
2. Which of the following drugs is used to treat helmenthiasis?
   1. Streptomycin
   2. Albendazole (Zentel)
   3. Penicillin
   4. Mebendazole (Pantelmin, Mebex, Wormin)
3. What is the basic structure of mebendazole and albendazole?
   1. Benzene ring
   2. Para amino benzoic acid ring
   3. Benzimidazole
   4. Pentane
4. What is the spectrum of both albendazole and mebendazole?
   1. Both broad spectrum
   2. Both narrow spectrum
   3. One narrow spectrum and one broad spectrum
   4. No spectrum
5. What is the mode of action of mebendazole and albendazole?
   1. Act on mitochondria, where they inhibit the anaerobic phosphorylation of ADP
   2. Inhibition of Acetyl cholinesterase
   3. Increase in calcium ion influx through cell membrane
   4. Act on microtubules in cytoskeleton where they block the transport of secretary granules and movement of other subcellular organelles
6. What are the adverse reactions of mebendazole?
   1. Skin rashes
   2. Nausea, abdominal pain, diarrhea
   3. Vertigo, dizziness, headache, arthralgia
   4. Hepatitis
7. What are the adverse reactions of albendazole?
   1. Alopecia, liver damage, bone marrow depression
   2. GI disturbances
   3. Vertigo, dizziness, headache, arthralgia
   4. Hepatitis
8. What are the therapeutic uses of mebendazole and albendazole?
   1. Ascariasis, ankylostomiasis, trichuriasis
   2. Hyatid disease, enterobiasis
   3. Cysticercosis, trichinella spiralis and strongyloidiasis
   4. Dysentery

Answers:

1. B
2. B,D
3. C
4. A
5. D
6. B,C
7. A,B
8. A,B,C

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