This is a quiz on the chemotherapy of trichomoniasis. A score of around 80% will ensure that you have good knowledge about this topic.

More than one option can be correct in any given question.

1. What is the causative agent for trichomoniasis?
   1. Trichomonas vaginalis (protozoa)
   2. E. coli (bacteria)
   3. Aspergillus (yeast)
   4. None of the above
2. Which part of the body does the organism infect?
   1. Vagina
   2. Gastric
   3. Vulva
   4. urethra
3. Which is the most commonly used drug?
   1. Streptomycin
   2. Penicillin
   3. Metronidazole
   4. Tetracycline
4. What is the basic structure of the drug?
   1. Benzene
   2. Beta lactam ring
   3. Amino group
   4. Nitroimidazole
5. What is the mechanism of action of the drug?
   1. Creates pores in the cell wall
   2. Inhibit protein synthesis
   3. Organism causes the reduction of 5′-nitro group of drug which results in the formation of short lived intermediates which can react with the DNA with lethal effect
   4. Causes the rupture of lysozyme
6. Drug is effective against which microbes?
   1. Anaerobic microbes
   2. Gram positive bacilli
   3. Gram negative rods
   4. Gram negative bacilli
7. What are the adverse reactions of drug?
   1. Nausea, anorexia, abdominal pain, metallic taste
   2. Headache, ataxia, urticaria
   3. Mild blood dyscrasias
   4. Tubular necrosis
8. What is the dosage of the drug?
   1. 400mg per day for 7-10 days followed by a second course after 4-6 weeks
   2. 400mg twice daily for 7-10 days followed by a second course after 4-6 weeks
   3. Single dose of 2 gm
   4. Two doses of 2 gm

Answers:

1. A
2. A,C,D
3. C
4. D
5. C
6. A,B,D
7. A,B,C
8. B, C

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